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A recent study highlights new mutations in the H5N1 bird flu virus across multiple states, raising concerns about the virus’s increased potential to spread between species and resist antiviral drugs. These mutations, though not immediately alarming, could heighten risk if they become widespread. The Department of Agriculture’s investigation, previously opaque, now provides insights into the virus’s evolution and transmission risks, emphasizing the need for continued surveillance and research to mitigate a possible broader outbreak and develop effective prevention strategies. The findings underscore the critical nature of understanding virus mutations to preemptively counter public health threats.